Progress in the understanding of the neurobiology of CUD has led to the discovery of several promising medications that have shown encouraging results in controlled clinical trials. CUD is a heterogeneous disorder that has so far not responded to pharmacotherapeutic interventions. Despite several decades of study, however, no medication has yet been approved for the treatment of CUD. This limitation has stimulated the search for pharmacological approaches for the treatment of CUD. Standard treatment for CUD has been associated with high dropout rates, and many patients do not attain substantial periods of cocaine abstinence. CM treatment has been found to be especially effective in promoting initial abstinence from cocaine.ĭespite progress in the development of psychosocial treatments for CUD, many patients still do not respond to these treatments. In this treatment, patients receive vouchers redeemable for goods and services in the community, contingent upon achieving a predetermined therapeutic goal. Perhaps the most effective psychosocial treatment for CUD is contingency management (CM), using voucher-based reinforcement. Cognitive behavioral therapy (CBT) and motivational interviewing have also been shown to be effective. Group counseling and individual drug counseling are the most common treatments. Several types of psychosocial treatments for CUD have proven efficacy. Development of effective treatments for CUD is therefore a clinical priority.īecause no medications have been approved for the treatment of CUD, psychosocial treatment is currently the standard treatment. Even in the current era of increasing opioid use and associated opioid overdose deaths, cocaine use remains a serious problem. However, deaths from cocaine overdose doubled between 20 ( 3) in non-Hispanic black men and women, the death rate from cocaine overdose exceeded that from opiate overdose ( 4). In the United States, the marked increase in overdose deaths in the past decade has been attributed largely to opioid overdose deaths.
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Use of cocaine, including crack cocaine, is associated with substantial morbidity and elevated rates of health care utilization ( 2), and deaths associated with cocaine use are increasing. With approximately 2.2 million regular users of cocaine in the United States, and 1 million individuals with cocaine use disorder (CUD) in the past year ( 1), CUD is a serious public health problem. Combination drugs may be especially promising. The most promising pharmacological strategies for CUD treatment thus far include the use of dopamine agonists, such as long-acting amphetamine and modafinil or glutamatergic and GABAergic agents such as topiramate. Despite these efforts, no medications have yet been proven to be safe and effective for the treatment of CUD. Consequently, investigators have sought to develop pharmacological agents to augment the efficacy of psychosocial treatments. However, the effect sizes of these treatments are not large, and they are not effective for most patients. Psychosocial treatments remain the treatments of choice for cocaine use disorder (CUD), with standard approaches including contingency management and cognitive behavioral therapy. Cocaine overdose deaths are increasing in the United States and, in certain populations, outnumber heroin and opiate overdose deaths. Cocaine abuse is associated with substantial morbidity and mortality. Plus, it’s more user friendly with its brand-new user interface and increased stability.Cocaine use continues to be a serious worldwide public health problem. Fishbowl 2011 offers new features, like cycle counting, report customizability and easy access to reports through a new favorites list.
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Many organizations looking to track their assets also use Fishbowl as a powerful standalone solution.įishbowl Inventory, the #1-Selling Inventory Management Software for QuickBooks, just got even better with the release of Fishbowl 2011. If you enjoy using QuickBooks as your accounting solution but need better inventory control, then Fishbowl Inventory is the answer for you! Fishbowl Inventory was one of the first programs to integrate with QuickBooks and currently holds Gold Developer Status, Intuit’s highest award for third-party integrators. Fishbowl Inventory is the #1-Selling Inventory Control Program for QuickBooks.